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Fitness evolution and the rise of mutator alleles in experimental Escherichia coli populations.

We studied the evolution of high mutation rates and the evolution of fitness in three experimental populations of Escherichia coli adapting to a glucose-limited environment. We identified the mutations responsible for the high mutation rates and show that their rate of substitution in all three popu...

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Detalhes bibliográficos
Main Authors: Shaver, Aaron C, Dombrowski, Peter G, Sweeney, Joseph Y, Treis, Tania, Zappala, Renata M, Sniegowski, Paul D
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462288/
https://ncbi.nlm.nih.gov/pubmed/12399371
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