Focused genetic recombination of bacteriophage t4 initiated by double-strand breaks.

A model system for studying double-strand-break (DSB)-induced genetic recombination in vivo based on the ets1 segCDelta strain of bacteriophage T4 was developed. The ets1, a 66-bp DNA fragment of phage T2L containing the cleavage site for the T4 SegC site-specific endonuclease, was inserted into the...

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Detalhes bibliográficos
Main Authors: Shcherbakov, Victor, Granovsky, Igor, Plugina, Lidiya, Shcherbakova, Tamara, Sizova, Svetlana, Pyatkov, Konstantin, Shlyapnikov, Michael, Shubina, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462285/
https://ncbi.nlm.nih.gov/pubmed/12399370
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