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Evaluating the impact of population bottlenecks in experimental evolution.

Experimental evolution involves severe, periodic reductions in population size when fresh media are inoculated during serial transfer. These bottlenecks affect the dynamics of evolution, reducing the probability that a beneficial mutation will reach fixation. We quantify the impact of these bottlene...

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Main Authors: Wahl, Lindi M, Gerrish, Philip J, Saika-Voivod, Ivan
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462272/
https://ncbi.nlm.nih.gov/pubmed/12399403
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