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Identification of 1088 new transposon insertions of Caenorhabditis elegans: a pilot study toward large-scale screens.

We explored the feasibility of a strategy based on transposons to generate identified mutants of most Caenorhabditis elegans genes. A total of 1088 random new insertions of C. elegans transposons Tc1, Tc3, and Tc5 were identified by anchored PCR, some of which result in a mutant phenotype.

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Detalhes bibliográficos
Main Authors: Martin, Edwige, Laloux, Hélène, Couette, Gaëlle, Alvarez, Thierry, Bessou, Catherine, Hauser, Oliver, Sookhareea, Satis, Labouesse, Michel, Ségalat, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462269/
https://ncbi.nlm.nih.gov/pubmed/12242258
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