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Efficient repair of DNA breaks in Drosophila: evidence for single-strand annealing and competition with other repair pathways.

We show evidence that DNA double-strand breaks induced in the Drosophila germ line can be repaired very efficiently by the single-strand annealing (SSA) mechanism. A double-strand break was made between two copies of a 1290-bp direct repeat by mobilizing a P transposon. In >80% of the progeny tha...

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Detalhes bibliográficos
Main Authors: Preston, Christine R, Engels, William, Flores, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462149/
https://ncbi.nlm.nih.gov/pubmed/12072467
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