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Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity.

Yeast MPT5 (UTH4) is a limiting component for longevity. We show here that MPT5 also functions to promote cell wall integrity. Loss of Mpt5p results in phenotypes associated with a weakened cell wall, including sorbitol-remedial temperature sensitivity and sensitivities to calcofluor white and sodiu...

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Detalhes bibliográficos
Main Authors: Kaeberlein, Matt, Guarente, Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461929/
https://ncbi.nlm.nih.gov/pubmed/11805047
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