Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival

The proteasome is the primary protease used by cells for degrading proteins and generating peptide ligands for class I molecules of the major histocompatibility complex. Based on the properties of cells adapted to grow in the presence of the proteasome inhibitor 4-hydroxy-5-iodo-3-nitrophenylacetyl-...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Princiotta, Michael F., Schubert, Ulrich, Chen, Weisan, Bennink, Jack R., Myung, Jayhyuk, Crews, Craig M., Yewdell, Jonathan W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14618/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11149939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.021132398
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