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Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival

The proteasome is the primary protease used by cells for degrading proteins and generating peptide ligands for class I molecules of the major histocompatibility complex. Based on the properties of cells adapted to grow in the presence of the proteasome inhibitor 4-hydroxy-5-iodo-3-nitrophenylacetyl-...

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Bibliografische gegevens
Hoofdauteurs: Princiotta, Michael F., Schubert, Ulrich, Chen, Weisan, Bennink, Jack R., Myung, Jayhyuk, Crews, Craig M., Yewdell, Jonathan W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14618/
https://ncbi.nlm.nih.gov/pubmed/11149939
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