SPO14 separation-of-function mutations define unique roles for phospholipase D in secretion and cellular differentiation in Saccharomyces cerevisiae.

In Saccharomyces cerevisiae, phospholipase D (PLD), encoded by the SPO14 gene, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid. SPO14 is essential for cellular differentiation during meiosis and is required for Golgi function when the normal secretory apparat...

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Main Authors: Rudge, S A, Pettitt, T R, Zhou, C, Wakelam, M J, Engebrecht, J A
格式: Artigo
語言:Inglês
出版: 2001
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461740/
https://ncbi.nlm.nih.gov/pubmed/11514437
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