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Statistical issues in the analysis of quantitative traits in combined crosses.

We consider some practical statistical issues in QTL analysis where several crosses originate in multiple inbred parents. Our results show that ignoring background polygenic variation in different crosses may lead to biased interval mapping estimates of QTL effects or loss of efficiency. Threshold a...

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Detalhes bibliográficos
Main Authors: Zou, F, Yandell, B S, Fine, J P
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461706/
https://ncbi.nlm.nih.gov/pubmed/11454780
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