A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans.

Most strains of Candida albicans undergo high frequency phenotypic switching. Strain WO-1 undergoes the white-opaque transition, which involves changes in colony and cellular morphology, gene expression, and virulence. We have hypothesized that the switch event involves heritable changes in chromati...

Full description

Saved in:
Bibliographic Details
Main Authors: Klar, A J, Srikantha, T, Soll, D R
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461676/
https://ncbi.nlm.nih.gov/pubmed/11404352
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items