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A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans.

Most strains of Candida albicans undergo high frequency phenotypic switching. Strain WO-1 undergoes the white-opaque transition, which involves changes in colony and cellular morphology, gene expression, and virulence. We have hypothesized that the switch event involves heritable changes in chromati...

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Main Authors: Klar, A J, Srikantha, T, Soll, D R
格式: Artigo
語言:Inglês
出版: 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461676/
https://ncbi.nlm.nih.gov/pubmed/11404352
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