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Expansions and contractions in 36-bp minisatellites by gene conversion in yeast.
The instability of simple tandem repeats, such as human minisatellite loci, has been suggested to arise by gene conversions. In Saccharomyces cerevisiae, a double-strand break (DSB) was created by the HO endonuclease so that DNA polymerases associated with gap repair must traverse an artificial mini...
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Main Authors: | , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2001
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1461658/ https://ncbi.nlm.nih.gov/pubmed/11333226 |
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