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Sequence and chromosomal context effects on variegated expression of keratin 5/lacZ constructs in stratified epithelia of transgenic mice.

The expression of transgene loci in mammals often occurs in a heterocellular fashion resulting in variegated patterns of expression. We have examined the effect of chromosomal integration site, copy number, and transcriptionally activating sequences on the variegation of a keratin 5-lacZ (K5Z) const...

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Hlavní autoři: Ramírez, A, Milot, E, Ponsa, I, Marcos-Gutiérrez, C, Page, A, Santos, M, Jorcano, J, Vidal, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461655/
https://ncbi.nlm.nih.gov/pubmed/11333242
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