A convenient approach to the synthesis of trinucleotide phosphoramidites--synthons for the generation of oligonucleotide/peptide libraries.

Trinucleotide phosphoramidites that correspond to the codons of all 20 amino acids were synthesized in high yield in 5g scale. Precursors of those amidites--trinucleotide phosphotriesters--have been prepared using the phosphotriester approach without protection of the 3'-hydroxyl function. The...

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Bibliographic Details
Main Authors: Kayushin, A L, Korosteleva, M D, Miroshnikov, A I, Kosch, W, Zubov, D, Piel, N
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC146157/
https://ncbi.nlm.nih.gov/pubmed/8871554
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