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Ethylnitrosourea-induced mutation in mice leads to the expression of a novel protein in the eye and to dominant cataracts.

A novel ENU-induced mutation in the mouse leading to a nuclear and zonular opacity of the eye lens (Aey1) was mapped to chromosome 1 between the markers D1Mit303 and D1Mit332. On the basis of the chromosomal position, the gamma-crystallin encoding gene cluster (Cryg) and the betaA2-crystallin encodi...

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Autors principals: Graw, J, Klopp, N, Löster, J, Soewarto, D, Fuchs, H, Becker-Follmann, J, Reis, A, Wolf, E, Balling, R, Habré de Angelis, M
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461562/
https://ncbi.nlm.nih.gov/pubmed/11238416
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