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A method for estimating the intensity of overdominant selection from the distribution of allele frequencies.

A method is proposed for estimating the intensity of overdominant selection scaled by the effective population size, S = 2Ns, from allele frequencies. The method is based on the assumption that, with strong overdominant selection, allele frequencies are nearly at their deterministic equilibrium valu...

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Detalhes bibliográficos
Main Authors: Slatkin, M, Muirhead, C A
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461383/
https://ncbi.nlm.nih.gov/pubmed/11102400
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