Function of tubulin binding proteins in vivo.

Overexpression of the beta-tubulin binding protein Rbl2p/cofactor A is lethal in yeast cells expressing a mutant alpha-tubulin, tub1-724, that produces unstable heterodimer. Here we use RBL2 overexpression to identify mutations in other genes that affect formation or stability of heterodimer. This a...

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Bibliographic Details
Main Authors: Fleming, J A, Vega, L R, Solomon, F
Format: Artigo
Language:Inglês
Published: 2000
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461238/
https://ncbi.nlm.nih.gov/pubmed/10978276
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