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Estimation of population parameters and recombination rates from single nucleotide polymorphisms.

Some general likelihood and Bayesian methods for analyzing single nucleotide polymorphisms (SNPs) are presented. First, an efficient method for estimating demographic parameters from SNPs in linkage equilibrium is derived. The method is applied in the estimation of growth rates of a human population...

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Bibliographic Details
Main Author: Nielsen, R
Format: Artigo
Language:Inglês
Published: 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460954/
https://ncbi.nlm.nih.gov/pubmed/10655242
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