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A stomatin and a degenerin interact to control anesthetic sensitivity in Caenorhabditis elegans.

The mechanism of action of volatile anesthetics is unknown. In Caenorhabditis elegans, mutations in the gene unc-1 alter anesthetic sensitivity. The protein UNC-1 is a close homologue of the mammalian protein stomatin. Mammalian stomatin is thought to interact with an as-yet-unknown ion channel to c...

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Bibliographic Details
Main Authors: Rajaram, S, Spangler, T L, Sedensky, M M, Morgan, P G
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460880/
https://ncbi.nlm.nih.gov/pubmed/10581275
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