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Kinetic studies on depurination and detritylation of CPG-bound intermediates during oligonucleotide synthesis.

Fully protected CPG-immobilized monomer, dimer and trimer oligonucleotides were used to study depurination during the chemical synthesis of oligonucleotides. Disappearance of the oligonucleotide during acid exposure time relative to an internal thymidine standard not subject to depurination was moni...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteur: Septak, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8760893/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.15.3053
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