Kinetic studies on depurination and detritylation of CPG-bound intermediates during oligonucleotide synthesis.
Fully protected CPG-immobilized monomer, dimer and trimer oligonucleotides were used to study depurination during the chemical synthesis of oligonucleotides. Disappearance of the oligonucleotide during acid exposure time relative to an internal thymidine standard not subject to depurination was moni...
Збережено в:
| Опубліковано в:: | Nucleic Acids Res |
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| Автор: | |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Oxford University Press
1996
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146050/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8760893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.15.3053 |
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