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Population dynamics of HIV-1 inferred from gene sequences.

A method for the estimation of population dynamic history from sequence data is described and used to investigate the past population dynamics of HIV-1 subtypes A and B. Using both gag and env gene alignments the effective population size of each subtype is estimated and found to be surprisingly sma...

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Autori principali: Grassly, N C, Harvey, P H, Holmes, E C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460489/
https://ncbi.nlm.nih.gov/pubmed/9927440
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