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Should we expect substitution rate to depend on population size?
The rate of nucleotide substitution is generally believed to be a decreasing function of effective population size, at least for nonsynonymous substitutions. This view was originally based on consideration of slightly deleterious mutations with a fixed distribution of selection coefficients. A reali...
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Formatua: | Artigo |
Hizkuntza: | Inglês |
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1998
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Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1460373/ https://ncbi.nlm.nih.gov/pubmed/9755219 |
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