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Gene silencing by DNA methylation and dual inheritance in Chinese hamster ovary cells.

Chinese hamster ovary (CHO) cells strain D422, which has one copy of the adenine phosphoribosyl transferase (APRT) gene, were permeabilized by electroporation and treated with 5-methyl deoxycytidine triphosphate. Cells with a silenced APRT gene were selected on 2, 6-diaminopurine. Colonies were isol...

詳細記述

保存先:
書誌詳細
主要な著者: Paulin, R P, Ho, T, Balzer, H J, Holliday, R
フォーマット: Artigo
言語:Inglês
出版事項: 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460210/
https://ncbi.nlm.nih.gov/pubmed/9611215
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