Structural Insights into the Assembly of the Type III Secretion Needle Complex

Type III secretion systems (TTSSs) mediate translocation of virulence factors into host cells. We report the 17-angstrom resolution structures of a central component of Salmonella typhimurium TTSS, the needle complex, and its assembly precursor, the bacterial envelope–anchored base. Both the base an...

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Bibliographic Details
Main Authors: Marlovits, Thomas C., Kubori, Tomoko, Sukhan, Anand, Thomas, Dennis R., Galán, Jorge E., Unger, Vinzenz M.
Format: Artigo
Language:Inglês
Published: 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459965/
https://ncbi.nlm.nih.gov/pubmed/15528446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1102610
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