An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae.

The PLC1 gene product of Saccharomyces cerevisiae is a homolog of the delta isoform of mammalian phosphoinositide-specific phospholipase C (PI-PLC). We found that two genes (SPL1 and SPL2), when overexpressed, can bypass the temperature-sensitive growth defect of a plc1delta cell. SPL1 is identical...

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Detaylı Bibliyografya
Asıl Yazarlar: Flick, J S, Thorner, J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1998
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459775/
https://ncbi.nlm.nih.gov/pubmed/9475719
Etiketler: Etiketle
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