Safety, Immunogenicity, and Efficacy of Prime-Boost Immunization with Recombinant Poxvirus FP9 and Modified Vaccinia Virus Ankara Encoding the Full-Length Plasmodium falciparum Circumsporozoite Protein

Heterologous prime-boost immunization with DNA and various recombinant poxviruses encoding malaria antigens is capable of inducing strong cell-mediated immune responses and partial protection in human sporozoite challenges. Here we report a series of trials assessing recombinant fowlpox virus and mo...

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Bibliografiska uppgifter
Huvudupphovsmän: Walther, Michael, Thompson, Fiona M., Dunachie, Susanna, Keating, Sheila, Todryk, Stephen, Berthoud, Tamara, Andrews, Laura, Andersen, Rikke F., Moore, Anne, Gilbert, Sarah C., Poulton, Ian, Dubovsky, Filip, Tierney, Eveline, Correa, Simon, Huntcooke, Angela, Butcher, Geoffrey, Williams, Jack, Sinden, Robert E., Hill, Adrian V. S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2006
Ämnen:
Fungal and Parasitic Infections
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459746/
https://ncbi.nlm.nih.gov/pubmed/16622207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2706-2716.2006
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