Bordetella pertussis Inhibition of Interleukin-12 (IL-12) p70 in Human Monocyte-Derived Dendritic Cells Blocks IL-12 p35 through Adenylate Cyclase Toxin-Dependent Cyclic AMP Induction

Bordetella pertussis, the causative agent of whooping cough, possesses an array of virulence factors, including adenylate cyclase toxin (ACT), relevant in the establishment of infection. Here we better define the impact of cyclic AMP (cAMP) intoxication due to the action of ACT on dendritic cell (DC...

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מידע ביבליוגרפי
Main Authors: Spensieri, Fabiana, Fedele, Giorgio, Fazio, Cecilia, Nasso, Maria, Stefanelli, Paola, Mastrantonio, Paola, Ausiello, Clara Maria
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2006
נושאים:
Host Response and Inflammation
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459734/
https://ncbi.nlm.nih.gov/pubmed/16622221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.2831-2838.2006
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