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Composition-Modified Matrices Improve Identification of Homologs of Saccharomyces cerevisiae Low-Complexity Glycoproteins

Yeast glycoproteins are representative of low-complexity sequences, those sequences rich in a few types of amino acids. Low-complexity protein sequences comprise more than 10% of the proteome but are poorly aligned by existing methods. Under default conditions, BLAST and FASTA use the scoring matrix...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Coronado, Juan E., Attie, Oliver, Epstein, Susan L., Qiu, Wei-Gang, Lipke, Peter N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459670/
https://ncbi.nlm.nih.gov/pubmed/16607010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.5.4.628-637.2006
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