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An Anion Antiporter Model of Prestin, the Outer Hair Cell Motor Protein

Cochlear amplification in mammalian hearing relies on an active mechanical feedback process generated by outer hair cells, driven by a protein, prestin (SLC26A5), in the lateral membrane. We have used kinetic models to understand the mechanism by which prestin might function. We show that the two pr...

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Bibliographic Details
Main Authors: Muallem, Daniella, Ashmore, Jonathan
Format: Artigo
Language:Inglês
Published: Biophysical Society 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459494/
https://ncbi.nlm.nih.gov/pubmed/16565043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.073254
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