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Two Isoforms of a Divalent Metal Transporter (DMT1) in Schistosoma mansoni Suggest a Surface-associated Pathway for Iron Absorption in Schistosomes

We describe two homologues of the mammalian divalent metal transporter (DMT1) for Schistosoma mansoni, a pathogenic intravascular parasite of humans. Schistosomes have a high nutritional and metabolic demand for iron. Nucleotide sequences of the parasite homologues, designated SmDMT1A and -B, are id...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Smyth, Danielle J., Glanfield, Amber, McManus, Donald P., Hacker, Elke, Blair, David, Anderson, Greg J., Jones, Malcolm K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459476/
https://ncbi.nlm.nih.gov/pubmed/16267047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M511148200
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