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Construction and properties of a herpes simplex virus 1 designed to enter cells solely via the IL-13α2 receptor

Current design of genetically engineered viruses for selective destruction of cancer cells is based on the observation that attenuated viruses replicate better in tumor cells than in normal cells. The ideal virus, however, is one that can infect only cancer cells by virtue of altered host range. Suc...

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Dettagli Bibliografici
Autori principali: Zhou, Guoying, Roizman, Bernard
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459385/
https://ncbi.nlm.nih.gov/pubmed/16554374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601258103
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