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Virulence of Leishmania major in macrophages and mice requires the gluconeogenic enzyme fructose-1,6-bisphosphatase

Leishmania are protozoan parasites that replicate within mature phagolysosomes of mammalian macrophages. To define the biochemical composition of the phagosome and carbon source requirements of intracellular stages of L. major, we investigated the role and requirement for the gluconeogenic enzyme fr...

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書誌詳細
主要な著者: Naderer, Thomas, Ellis, Miriam A., Sernee, M. Fleur, De Souza, David P., Curtis, Joan, Handman, Emanuela, McConville, Malcolm J.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459384/
https://ncbi.nlm.nih.gov/pubmed/16569701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509196103
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