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Virulence of Leishmania major in macrophages and mice requires the gluconeogenic enzyme fructose-1,6-bisphosphatase

Leishmania are protozoan parasites that replicate within mature phagolysosomes of mammalian macrophages. To define the biochemical composition of the phagosome and carbon source requirements of intracellular stages of L. major, we investigated the role and requirement for the gluconeogenic enzyme fr...

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Bibliografische gegevens
Hoofdauteurs: Naderer, Thomas, Ellis, Miriam A., Sernee, M. Fleur, De Souza, David P., Curtis, Joan, Handman, Emanuela, McConville, Malcolm J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459384/
https://ncbi.nlm.nih.gov/pubmed/16569701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509196103
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