MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

Adipocytes secrete a variety of bioactive molecules that affect the insulin sensitivity of other tissues. We now show that the abundance of monocyte chemoattractant protein–1 (MCP-1) mRNA in adipose tissue and the plasma concentration of MCP-1 were increased both in genetically obese diabetic (db/db...

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Autors principals: Kanda, Hajime, Tateya, Sanshiro, Tamori, Yoshikazu, Kotani, Ko, Hiasa, Ken-ichi, Kitazawa, Riko, Kitazawa, Sohei, Miyachi, Hitoshi, Maeda, Sakan, Egashira, Kensuke, Kasuga, Masato
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459069/
https://ncbi.nlm.nih.gov/pubmed/16691291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26498
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