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Lung dysfunction causes systemic hypoxia in estrogen receptor β knockout (ERβ(−/−)) mice

Estrogen receptor β (ERβ) is highly expressed in both type I and II pneumocytes as well as bronchiolar epithelial cells. ERα is not detectable in the adult lung. Lungs of adult female ERβ knockout (ERβ(−/−)) mice have already been reported to have fewer alveoli and reduced elastic recoil. In this ar...

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Autores principales: Morani, Andrea, Barros, Rodrigo P. A., Imamov, Otabek, Hultenby, Kjell, Arner, Anders, Warner, Margaret, Gustafsson, Jan-Åke
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459034/
https://ncbi.nlm.nih.gov/pubmed/16636272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602194103
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