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Weak selection and recent mutational changes influence polymorphic synonymous mutations in humans

Recent large-scale genomic and evolutionary studies have revealed the small but detectable signature of weak selection on synonymous mutations during mammalian evolution, likely acting at the level of translational efficacy (i.e., translational selection). To investigate whether weak selection, and...

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Detalhes bibliográficos
Autor principal: Comeron, Josep M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458998/
https://ncbi.nlm.nih.gov/pubmed/16632609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510638103
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