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Sequence composition effects on the stabilities of triple helix formation by oligonucleotides containing N7-deoxyguanosine.
A nonnatural nucleoside, 7-(2-deoxy-beta-D-erythro-pento-furanosyl)-guanine (d7G), mimics protonated cytosine and specifically binds GC base pairs within a pyrimidine - purine - pyrimidine triple helix. The differences in association constants (KT) determined by quantitative footprint titration expe...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1996
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145894/ https://ncbi.nlm.nih.gov/pubmed/8668526 |
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