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Monitoring chaperone engagement of substrates in the endoplasmic reticulum of live cells

The folding environment in the endoplasmic reticulum (ER) depends on multiple abundant chaperones that function together to accommodate a range of substrates. The ways in which substrate engagement shapes either specific chaperone dynamics or general ER attributes in vivo remain unknown. In this stu...

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Detalles Bibliográficos
Main Authors: Snapp, Erik L., Sharma, Ajay, Lippincott-Schwartz, Jennifer, Hegde, Ramanujan S.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458919/
https://ncbi.nlm.nih.gov/pubmed/16617114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510657103
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