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Crystal structures of γ-glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate

γ-Glutamyltranspeptidase (GGT) is a heterodimic enzyme that is generated from the precursor protein through posttranslational processing and catalyzes the hydrolysis of γ-glutamyl bonds in γ-glutamyl compounds such as glutathione and/or the transfer of the γ-glutamyl group to other amino acids and p...

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Autori principali: Okada, Toshihiro, Suzuki, Hideyuki, Wada, Kei, Kumagai, Hidehiko, Fukuyama, Keiichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458908/
https://ncbi.nlm.nih.gov/pubmed/16618936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511020103
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