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Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin

Non-small cell lung cancer (NSCLC) demonstrates a strong etiologic association with smoking. Although nicotine is not carcinogenic, it can induce cell proliferation and angiogenesis and suppress apoptosis induced by certain agents. Here we show that nicotine inhibits apoptosis induced by the drugs g...

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Detalhes bibliográficos
Main Authors: Dasgupta, Piyali, Kinkade, Rebecca, Joshi, Bharat, DeCook, Christina, Haura, Eric, Chellappan, Srikumar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458878/
https://ncbi.nlm.nih.gov/pubmed/16601104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509313103
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