Proteasomes shape the repertoire of T cells participating in antigen-specific immune responses

Differences in the cleavage specificities of constitutive proteasomes and immunoproteasomes significantly affect the generation of MHC class I ligands and therefore the activation of CD8-positive T cells. Based on these findings, we investigated whether proteasomal specificity also influences CD8-po...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Osterloh, Philipp, Linkemann, Kathrin, Tenzer, Stefan, Rammensee, Hans-Georg, Radsak, Markus P., Busch, Dirk H., Schild, Hansjörg
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2006
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458791/
https://ncbi.nlm.nih.gov/pubmed/16549793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509256103
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