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Pertactin β-helix folding mechanism suggests common themes for the secretion and folding of autotransporter proteins

Many virulence factors secreted from pathogenic Gram-negative bacteria are autotransporter proteins. The final step of autotransporter secretion is C → N-terminal threading of the passenger domain through the outer membrane (OM), mediated by a cotranslated C-terminal porin domain. The native structu...

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Hlavní autoři: Junker, Mirco, Schuster, Christopher C., McDonnell, Andrew V., Sorg, Kelli A., Finn, Mary C., Berger, Bonnie, Clark, Patricia L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458770/
https://ncbi.nlm.nih.gov/pubmed/16549796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507923103
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