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Pertactin β-helix folding mechanism suggests common themes for the secretion and folding of autotransporter proteins
Many virulence factors secreted from pathogenic Gram-negative bacteria are autotransporter proteins. The final step of autotransporter secretion is C → N-terminal threading of the passenger domain through the outer membrane (OM), mediated by a cotranslated C-terminal porin domain. The native structu...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458770/ https://ncbi.nlm.nih.gov/pubmed/16549796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507923103 |
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