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Oligodeoxynucleoside phosphoramidates (P-NH2): synthesis and thermal stability of duplexes with DNA and RNA targets.

Syntheses of non ionic oligodeoxynucleoside phosphoramidates (P-NH2) and mixed phosphoramidate- phosphodiester oligomers were accomplished on automated solid supported DNA synthesizer using both H-phosphonate and phosphoramidite chemistries, in combination with t-butylphenoxyacetyl for N-protection...

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Udgivet i:Nucleic Acids Res
Principais autores: Peyrottes, S, Vasseur, J J, Imbach, J L, Rayner, B
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145873/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8657564/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.10.1841
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