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Retinoic acid signaling and the evolution of chordates

In chordates, which comprise urochordates, cephalochordates and vertebrates, the vitamin A-derived morphogen retinoic acid (RA) has a pivotal role during development. Altering levels of endogenous RA signaling during early embryology leads to severe malformations, mainly due to incorrect positional...

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Detalles Bibliográficos
Main Authors: Marlétaz, Ferdinand, Holland, Linda Z., Laudet, Vincent, Schubert, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458431/
https://ncbi.nlm.nih.gov/pubmed/16733532
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