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Protein cleavage strategies for an improved analysis of the membrane proteome

BACKGROUND: Membrane proteins still remain elusive in proteomic studies. This is in part due to the distribution of the amino acids lysine and arginine, which are less frequent in integral membrane proteins and almost absent in transmembrane helices. As these amino acids are cleavage targets for the...

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Detalhes bibliográficos
Main Authors: Fischer, Frank, Poetsch, Ansgar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458320/
https://ncbi.nlm.nih.gov/pubmed/16512920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-4-2
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