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HPP1: A transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers

Adenomas are the precursors of most colorectal cancers. Hyperplastic polyps have been linked to the subset of colorectal cancers showing DNA microsatellite instability, but little is known of their underlying genetic etiology. Using a strategy that isolates differentially methylated sequences from h...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Young, Joanne, Biden, Kelli G., Simms, Lisa A., Huggard, Phillip, Karamatic, Rozemary, Eyre, Helen J., Sutherland, Grant R., Herath, Nirmitha, Barker, Melissa, Anderson, Gregory J., Fitzpatrick, David R., Ramm, Grant A., Jass, Jeremy R., Leggett, Barbara A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14579/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120884/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.1.265
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