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Suppression of HIV replication in the resting CD4(+) T cell reservoir by autologous CD8(+) T cells: Implications for the development of therapeutic strategies

CD8(+) T cell-mediated antiviral activity against HIV has been described consistently in infected individuals; however, the role of this activity in controlling replication of HIV in the latently infected, resting CD4(+) T cell reservoir is unclear. By using an ex vivo system, we show that replicati...

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Uloženo v:
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Chun, Tae-Wook, Justement, J. Shawn, Moir, Susan, Hallahan, Claire W., Ehler, Linda A., Liu, Shuying, McLaughlin, Mary, Dybul, Mark, Mican, JoAnn M., Fauci, Anthony S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2001
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14577/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11136258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.1.253
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