Effects of cyclophosphamide on the in vivo response of outbred athymic (nude) mice to a thymus-independent antigen (DNP-AGG-Ficoll).

Both nude mice (nu/nu) and their heterozygous littermates (nu/+) were injected with a single IP dose of 300 mg cyclophosphamide (CY)/kg. CY is a known immunosuppressive agent, which affects primarily B lymphocytes. Immunization with the thymus independent antigen DNP-AGG59-Ficoll after CY treatment...

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Bibliographic Details
Main Authors: Snippe, H, Merchant, B, Johannessen, L, Inman, J K
Format: Artigo
Language:Inglês
Published: 1978
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1457445/
https://ncbi.nlm.nih.gov/pubmed/367956
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