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Unusual resistance of ALR/Lt mouse β cells to autoimmune destruction: Role for β cell-expressed resistance determinants

Genetic analysis of autoimmune insulin-dependent diabetes mellitus (IDDM) has focused on genes controlling immune functions, with little investigation of innate susceptibility determinants expressed at the level of target β cells. The Alloxan (AL) Resistant (R) Leiter (Lt) mouse strain, closely rela...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Proc Natl Acad Sci U S A
Ngā kaituhi matua: Mathews, Clayton E., Graser, Robert T., Savinov, Alexei, Serreze, David V., Leiter, Edward H.
Hōputu: Artigo
Reo:Inglês
I whakaputaina: National Academy of Sciences 2001
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14574/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11136257/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.1.235
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