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Organophosphorus inhibition of lysosomal enzyme secretion from polymorphonuclear leucocytes. Evidence of a lack of a requirement for esterase activation.
Previously, di-isopropylphosphorofloridate (DFP) was shown to inhibit the release of lysosomal enzymes induced by chemotactic factors. It was suggested that the inhibition was due to the phosphorylation of a cell bound serine esterase activated by the chemotactic factor. However, as shown here, di-i...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1978
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1457262/ https://ncbi.nlm.nih.gov/pubmed/750374 |
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