A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications

Compared with other sequenced animal genomes, human segmental duplications appear larger, more interspersed, and disproportionately represented as high-sequence identity alignments. Global sequence divergence estimates of human duplications have suggested an expansion relatively recently during homi...

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Hlavní autoři: She, Xinwei, Liu, Ge, Ventura, Mario, Zhao, Shaying, Misceo, Doriana, Roberto, Roberta, Cardone, Maria Francesca, Rocchi, Mariano, Green, Eric D., Archidiacano, Nicoletta, Eichler, Evan E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2006
Témata:
Letter
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1457043/
https://ncbi.nlm.nih.gov/pubmed/16606706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.4949406
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