Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice

BACKGROUND: Asthma is associated with airway hyperresponsiveness and enhanced T-cell number/activity on one hand and increased levels of exhaled nitric oxide (NO) with expression of inducible NO synthase (iNOS) on the other hand. These findings are in paradox, as NO also relaxes airway smooth muscle...

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Detalhes bibliográficos
Main Authors: Broeke, Robert Ten, De Crom, Rini, Van Haperen, Rien, Verweij, Vivienne, Leusink-Muis, Thea, Van Ark, Ingrid, De Clerck, Fred, Nijkamp, Frans P, Folkerts, Gert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456969/
https://ncbi.nlm.nih.gov/pubmed/16597326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-58
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